Bricks and mortar could adapt. For instance, let's take the bookshop for people to come and do what he terms "showrooming" (looking at a book, then buying it online.) What if the store was made
explicitly for that purpose ?
You wouldn't need a large room at the back to house 10 or 50 or 200 copies of the book, just one copy out front. The book on display may not even have to be the real book, just a slim cover, some info, and a QR or similar code to scan to get the info and make a purchase if you like on your electronic device of choice (e-reader, phone or tablet.)
The store could also re-design itself for it's new purpose. People like to be in bookshops in order to meet other people who like to go to bookshops. So, the store could focus on the "coffee" aspect, that is use the saved space to make comfortable seating and meeting locations, with pleasant snacks and beverages to hand for some profit.
There could also be merchandise from the popular books too, posters and t-shirts and what have you. Perhaps the store might be owned by Amazon, or perhaps there might be some sort of licensing deal struck whereby the store would be able to make some profit from books purchased after people had checked them out there.
Hosted events could also be held, book signings and the like, which again would bring the chance to sell more coffee and the like. In fact, the store would become primarily a coffee shop, oriented on profit from that, and the socializing that people like to go to those stores for. Starbucks could start doing it, but they'd need larger stores of course as most are very small, but the move could come from that side of the industry.
Knowledgeable staff would be another plus not provided online. "When is the next Starbringers of Mighty Doom Orc Warriors due out?" "I really liked The Time Just After The Sun Sets But Before It Gets Really Dark, what else might I like?"
The product would change - no longer would they aim to move physical copies of the books, but instead provide services, a meeting place, and the sale of coffee and soft drinks.
Specialist software could be developed for the store, with an app for your device. This could let people have a "forum" there, physically located in the store in a sense, but not requiring people to be online at the same time. People could leave messages, or reviews. Augmented Reality could be used for some interesting marketing and promo stuff. Your little slim fake book could, once selected in the app, prompt you about the book, telling you about movies and tv series' it is based on or inspired, even letting you watch snippets and extracts on your device, and giving you the opportunity to book tickets to a showing, rent the movie, purchase the DVD, purchase the music used in the show, etc. It could cross-connect you to other works listed by the author as inspirations or their favorites.
Personally, I really like that kind of idea