There is weak panspermia and strong panspermia (kind of like the anthropic principle). Strong panspermia posits actual life coming to Earth, and I agree that's just a layer of turtles.
Weak panspermia, OTOH, doesn't posit life as such, but pre-life biological chemical units. And some fairly complicated chemistry has been detected in space, both spectroscopically and by analysis of comets. So the idea is that complex chemistry develops in space, where there's a lot of raw materials, energy, and time, and rains down on protoplanets. Most of the early stuff gets toasted, but once the planet cools enough, this prebiological soup becomes the basis for the development of life.
If you assume (not a given, but a reasonable assumption) that DNA and other aspects of our biology are inevitable, given the way chemistry works, then it is quite possible that life on widely separated planets could resemble each other, at least at the subcellular level. It doesn't mean we could interbreed with Romulans, but it does mean we might be able to eat them. And vice-versa, unfortunately.