Yeah, or how about a post-federation future after a economic or social collapse after a golden age. And ships have to navigate through hyperspace minefields so many are afraid to travel and many different earth colonies are cut off from each other, and the solar system is in civil war. And the Vulcans have just disappeard for some unknown reason. Maybe humanity crossed some line and ticked off a Q like race and all these things were done to send humans back to a darker age but a group of scavengers fly around in a Federation/Romulan Hybrid and some human colonies would die out if it weren't for hand outs from the prosperous klingon empire. This is just off the top of my head but I think "bold" ideas can revive star trek so many new "bold" writer's can "boldly" take things in a "bold" new direction.
