Let's see, best ever, of all time? I can only tell you how I feel about that currently, likely in two days I will have changed my mind if not slightly, then entirely. But here goes.
In best game order (1=best)
1. Grand Theft Auto: San Andreas
Simply the best game of all time. One of those pick up and play games, where you can pretty much do whatever you want, whenever you want.
2. Sim City 4
Okay, so the arcologies were apparently removed from the game, but still a great game that stands the test of time, and allows you to build cities that supply each other. Another one of those pick up and play games.
I'm too drunk with beer and football to continue, sorry...