Likely developments in the next two hundred years?
1. Practical immortality
2. Fusion.
3. Machine-biological interface
4. External gestation of babies.
5. Quantum computers.
I think we can reasonably expect those developments from research and development happening now.
Given that few if any predicted the information revolution then something could develop from left field. That something would have to be FTL in some form if we are to even escape this solar system.