I agree that his personal boredom means he is the one who's exhausted, not the genre. True, there are exhausted tropes in SF, and at times SF clearly needs to work harder to move beyond those old tropes. But the same is true for most genres... in fact, that's what usually makes them genres.
I think basing his opinion on "best of" lists is his mistake, as those lists (in SF) tend to be pretty typical, trope-rich stuff. And they are typically from recognized names; not a lot of new authors in there. That's a recipe for same-old, same-old.
He... and most of the rest of the industry... needs to look further afield, for the new and unestablished talent that brings the new blood to SF. Innovation will come from tomorrow's authors, not yesterday's.