Another problem with autonomous cargo drones (even more so autnomous vehicles) might be their potential for nefarious use. A self-driving taxi could easily be made into a (rather slow) GPS-guided missile. To avoid detection, stuff the HE into a tailor's dummy - although I imagine self-driving taxis will be quite intensively used as small freight vehicles, anyway, so an apparently empty vehicle wouldn't be all that suspicious. Especially as they will probably move around (to holding areas, perhaps?) when not in use, anyway.