I agree that the big picture corrections are important. Honestly all these points are important and I think it comes down to what you want from a beta reader. Like critical responses, sometimes its useful and other times detrimental.
I work with my editor and she is most harsh with points relating to clarity. If something does not easily make sense she will protest her confusion.
I started this thread because at that point I actually had a bad experience with one of my beta readers.
He was a friend and a close one at that. When he told me he wanted to beta read my work I wasn't even 20 thousand words into my first rough draft. I should have said no and polished it more first, before handing it over as I did with my later beta readers.
His critical response to my "raw" work was not so much scathing but made me realise you have to work a lot harder on your ms before a beta should even touch it.
I think my point of view on it now is that beta readers should point out anything, so long as I feel like I have polished the work enough to plop before them then fairs fair and I can take it.